CheckMate 026: Why did Opdivo (nivolumab) fail in NSCLC?

September 1, 2016- Interviewed by Steven E. Greer, MD

In the wake of the news-making failure of CheckMate 026 of Bristol-Myers Squibb’s Opdivo (nivolumab) fail in NSCLC, we interviewed Siwen Hu-Lieskovan MD, PhD, an expert in immunotherapy, about the trial design. She believes that the trial design is the reason for failure rather than the drug not working. A second Phase 3 trial is underway now that is better designed, she thinks.

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